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Giuseppe Puglisi

Professori Ordinari
tel: +390805963744
e-mail: giuseppe.puglisi@poliba.it

 


Pubblicazioni scientifiche

Elenco pubblicazioni presenti nel  Catalogo dei prodotti della Ricerca

 


Collaborazioni internazionali

We develop microscopic-based models aiming at the description of the effect of forces, entropic terms and loading rate in a wide range of biological and bioinspired materials and phenomena, such as DNA denaturation, tropollagen fibers, neuronal axons or unfolding in moleculs. Based on the constitutive laws obtained at this microscopic scale, the aim is to derive multiscale equations describing the overall macroscopic response of such systems.

  • Prof. Alain Goriely (University of Oxford) - Oxford (REGNO UNITO)

We develop models where microscopic instabilities can induce nucleation and propagation of defects, fracture and phase transformation phenomena observed in systems such as shape memory nanowires and composite materials. We consider the effects of temperature and the role of local and non-local interactions also including softening mechanisms.

  • Stefano Giordano (Université de Lille) - Lille (FRANCIA)

We develop models for electro-active polymers in order to use them to obtain metamaterials with innovative mechanical properties or in the context of artificial muscles where one can take advantage of their features such as large strain and damage tolerance. Further applications of these systems are related to microfluidics actuators: in this case one can apply a bias voltage to the electroactive polymer in order to control the shape of a microfluidic channel.

  • Michel Destrade (University of Galway) - Galway (IRLANDA)
  • Giuseppe Zurlo (University of Galway) - Galway (IRLANDA)

We develop coarse-grained models to predict folding, native states, energy barriers, protein unfolding, mutations and other structural properties of proteins. We aim at the description of phenomena that are out of the range of classical molecular modeling approaches due to the large computational cost: multi-molecular interactions, cyclic behavior under variable external interactions. Within this framework we group the amino acids sequence in a smaller number of elements. Nearest neighbor energy terms are then introduced to reproduce the interaction of such amino acid groups. Nearest and non-nearest neighbor energy terms, inter and intra functional blocks are added to reproduce important properties of the folding-unfolding mechanical response, including the monotonic and cyclic force-elongation behavior.

  • Markus J. Buehler (Massachusetts Institute of Technology) - Boston (STATI UNITI D'AMERICA)